超微血管成像与超声造影评价颈动脉斑块内新生血管的对比研究

Assessment of carotid artery plaque neovascularization by superb micro-vascular imaging and contrast-enhanced ultrasound

目的探讨对比超微血管成像(superb micro-vascular imaging,SMI)与超声造影(contrast-enhanced ultrasound,CEUS)技术对颈动脉粥样硬化斑块内新生血管显示的价值。方法选取69例颈动脉粥样硬化斑块患者,接受彩色多普勒超声和SMI检查,其中35例接受超声造影检查,记录颈动脉粥样硬化斑块数量、位置、厚度、回声强度、表面形态、有无溃疡、钙化及颈动脉管腔狭窄等,利用SMI和CEUS分别观察斑块内新生血管情况,记录新生血管的部位、形态、数量并评分,评价SMI和CEUS结果的一致性。结果 SMI显示斑块内新生血管评分:0分18例,1分26例,2分25例;CEUS显示斑块内新生血管评分:0分7例,1分13例,2分15例;SMI和CEUS评分有较好的一致性(kappa=0.689,P<0.05)。结论SMI检测颈动脉斑块内新生血管与CEUS结果具有良好的一致性,SMI技术可作为颈动脉斑块内新生血管首选的影像学检查方法。

Objective To evaluate the value of superb micro-vascular imaging （SMI） on neovascularization of carotid athero- sclerosis plaque contrast by contrast-enhanced uhrasound （CEUS）. Methods A total of 69 patients with carotid atherosclerotic plaques accepted color Doppler flow imaging （CDFI） and SMI. Of them, 35 cases were examined by contrast-enhanced ultrasound （CEUS） and ultrasonic features （including the number of carotid atheroselerotic plaques, position, thickness, echo, surface and ulcer, and carotid artery stenosis were recorded. Assessment of carotid artery plaque neovascularization （ including the position, shape, number, evaluation and consistency of SMI and CEUS） obtained by SMI and CEUS respectively were documented and ana- lyzed. The neovascularization within the plaque was categorized as grade 0 to grade 2. Results SMI ： The score of 18 cases about neovascularization in plaque were 0, 26 cases were 1, 25 cases were 2 ; CEUS ： The score of 7 cases about neovascularization in plaque were 0, 13 cases were 1, 15 cases were 2. It had good consistency between SMI and CEUS （kappa =0. 689, P 〈0.05）. Conclusion In detecting carotid artery plaque neovascularization, it has good consistency between SM1 and CEUS. SMI can be used as first choice in detecting carotid plaques neovascularization.