发作性睡病患者的血清EB病毒回顾性分析研究

The Analysis of results from EB Virus Serological Examination of Patients with Narcolepsy

目的:通过搜集中国中医科学院广安门医院睡眠医学专题门诊发作性睡病患者数据,初步描述血清EB病毒检测结果情况。方法:选取科室于2014年3月27日至2017年8月29日收治的503例发作性睡病患者EB病毒血清检测结果,进行回顾性分析。结果:发作性睡病患者的EBV-CA-IgG、EBV-CA-IgM、EBV-NA-IgG、EBV-EA-IgM阳性率分别为91.7%、3.0%、90.7%、2.4%,86.88%,患者的血清EB病毒检测以EBV-CA-IgG与EBV-NA-IgG同时阳性为主,全阴性为次。结论:EBV可能是发作性睡病的重要发病因素。

Objective： By collecting the data of the patients with narcolepsy in Guang＇anmen Hospital of China Academy of Chinese Medical Sciences,a preliminary descriptionof the EB Virus serological examinations was made. Methods：Collect EBV data of 503 patients diagnosed with Narcolepsy between March 27 th 2013 and August 29 th 2017,and take the retrospective analysis. Results： The positive rate of EBV-CA-IgG、EBV-CA-IgM、EBV-NA-IgG and EBV-EA-IgM were91. 7%,3. 0%,90. 7%,2. 4%. 86. 88%,most patients were simultaneously positive of EBV-CA-IgG and EBV-NAIgG. And the incidence of all negative was at the second place. Conclusion： EBV may be an important pathogenic factor of narcolepsy,and it is an important reference index for prognosis and rehabilitation.