超声光散射断层成像技术对亚厘米级乳腺肿瘤的诊断价值(附98例分析)

Diagnostic value of diffuse optical tomography(DOT)in sub-centimeter breast tumors:Analysis of 98 cases

目的联合应用常规超声及超声光散射断层成像技术(DOT),探讨其在亚厘米级(≤1cm)乳腺肿块良恶性诊断中的临床价值。方法选择本院行外科手术或穿刺活检的住院女性患者98例,112个≤1cm的乳腺肿块。应用常规超声与DOT进行检查,计算常规超声、DOT及两种方法联合诊断乳腺肿块的敏感性、特异性、阳性预测值、阴性预测值、准确性。结果常规超声、DOT及两种方法联合诊断乳腺肿块的敏感性、特异性、阳性预测值、阴性预测值、准确性分别是:常规超声为63.63%、91.11%、63.63%、91.11%和85.71%,DOT为63.63%、93.33%、70%、91.3%和87.5%,两者联合为81.81%、95.56%、81.81%、95.56%和92.86%。结论联合常规超声与DOT能够提高亚厘米级(≤1cm)乳腺癌诊断的准确性,值得临床上推广。

Objective To evaluate the value of ultrasonography combined with diffuse optical tomography （DOT） in the diagnosis of malignant masses of sub-centimeter breast masses （41 cm） , Methods The imaging data of 112 pathologically were proven breast masses on ultrasound and DOT were analyzed. Examination of the breast lesions were observed by ultra- sonography and DOT. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the diagnostic value were calculated by using ultrasound, DOT and both methods. Results Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 63.63%, 91.11%, 63.63%, 91.11%, 85.71% in diagnosis of ultrasound, 63.63%, 93.33%, 70%, 91.3%, 87.5% in diagnosis of DOT and 81.81%, 95.56%, 81.81%, 95.56%, 92.86% indiagnosis of ultrasound combined with DOT, respectively. Conclusion Ultrasound combined with DOT can improve the accuracy of diagnosis in sub-centimeter breast masses （41 cm）, which is worth promoting clinically.