22855例真菌病患者病种及其致病菌种分析

Analysis of mycoses and pathogenic fungi in 22 855 patients with fungal infection

目的:明确我院就诊患者中真菌病种及其致病菌种的分布。方法:对我院皮肤性病门诊2012年4月至2016年8月拟诊为真菌感染的65 751例患者中真菌检查阳性的患者临床资料及分离的致病菌株资料进行回顾性分析。结果:65 751例中直接镜检和(或)培养阳性22 855例,阳性率35%。共包括11个病种,患病人数前三位的病种为足癣5054例,甲真菌病3866例,股癣3071例。共分离出致病真菌5884株,前三位为红色毛癣菌3794株(64.46%),念珠菌943株(16.03%),第三是须癣毛癣菌复合体558株(9.48%)。结论:我院真菌病患者中足癣、甲真菌病和股癣是最重要的病种,常见菌种为毛癣菌和念珠菌。

Objective： To determine the mycoses and pathogenic fungi species in 65 751 patients from Shandong Provincial Hospital for Skin Diseases. Methods： The clinical data of patients who tested positive for fungi were retrospectively analyzed. Results： Out of 65 751 patients,22 855 patients was positive for fungi by direct microscopy and/or culture,giving a positivity rate of 35%. There were 11 kinds of diseases and the most common diseases were tinea pedis（ 5054 patients）,followed by onychomycosis（ 3866 patients） and tinea cruris（ 3071 patients）. Five thousand eight hundred and eighty four strains were isolated and the most were T.rubrum（ 3794 strains（ 64.46%）,followed by Candida 943 strains（ 16.03%） and T. mentagrophytes complex558 strains（ 9. 48%）. Conclusion： The mopst common fungal diseases are tinea pedis,onychomycosis and tinea cruris and the most common causative agents are trichophyta and Candida species in our hospital.