妊娠期贫血患者的RBC、HCT及Ret水平变化临床治疗研究

Study on the changes of RBC,Hct,and Ret levels in patients with anemia during pregnancy and clinical treatment

目的探讨妊娠期贫血患者的RBC、HCT、Ret水平变化及应对治疗的方案。方法选择808例妊娠期贫血患者随机分为对照组和观察组各404例,对照组患者运用多糖铁复合物胶囊进行治疗,观察组患者运用蔗糖铁注射液进行治疗。对两组患者治疗前、后红细胞(RBC)、红细胞占全血容积百分比(HCT)、网织红细胞百分比(Ret)水平以、血清血红蛋白(Hb)、铁蛋白(SF)及血清铁(SI)水平进行对比分析,比较两组患者临床治疗效果以及不良分娩结果的发生率。结果两组患者治疗后RBC、HCT以及Ret水平显著优于治疗前,并且治疗后观察组患者RBC、HCT以及Ret水平显著优于对照组,差异均有统计学意义(P<0.05)。两组患者治疗后Hb、SF及SI水平显著优于治疗前,并且治疗后观察组患者Hb、SF及SI水平显著优于对照组,差异均有统计学意义(P<0.05)。观察组患者治疗的有效率显著高于对照组,不良分娩结局率显著低于对照组,差异均有统计学意义(P<0.05)。结论采用蔗糖铁注射液对妊娠期贫血患者进行治疗能显著改善患者RBC、HCT、Ret及Hb、SF、SI水平,显著提高患者的临床治疗效果,降低患者不良分娩结局率的发生。

Objective To explore the changes of red blood cells（ RBC）,hematocrit（ Hct）,and reticulocyte percentage（ Ret） levels in patients with anemia during pregnancy and coping strategies. Methods A total of 808 patients with anemia during pregnancy were selected and randomly divided into control group and observation group,404 patients in each group. The patients in control group were treated by polysaccharide iron complex capsules,and the patients in control group were treated by sucrose iron injection. The levels of RBC,Hct,Ret,serum hemoglobin（ Hb）,serum ferritin（ SF）,and serum iron（ SI）,clinical effects,and incidence rates of adverse delivery outcomes in the two groups were compared and analyzed. Results After treatment,the levels of RBC,Hct,and Ret in the two groups were significantly better than those before treatment,and the levels of RBC,Hct,and Ret in observation group were significantly better than those in control group（ P〈0. 05）. After treatment,the levels of Hb,SF,and SI in the two groups were significantly better than those before treatment,and the levels of Hb,SF,and SI in observation group were significantly better than those in control group（ P〈0. 05）. The effective rate of treatment in observation group was significantly higher than that in control group（ P〈0. 05）,and the incidence rate of adverse delivery outcomes in observation group was significantly lower than that in control group（ P〈0. 05）. Conclusion Sucrose iron injection can significantly improve the levels of RBC,Hct,Ret,Hb,SF,and SI,enhance the clinical effect,and reduce the incidence rate of adverse delivery outcomes in treatment of patients with anemia during pregnancy.