沈阳地区2011-2016年青光眼住院患者构成及特点分析

Characteristics of hospitalized patients with glaucoma in Shenyang

目的了解沈阳地区2011-2016年青光眼住院患者的构成及变化特点。设计回顾性病例系列。研究对象2011年11月1日至2016年10月31日沈阳市第四人民医院住院的18周岁及以上的青光眼患者。方法对患者病例资料进行回顾性分析。根据出院诊断将其分为原发性闭角型青光眼(primary angle closure glaucoma,PACG)、原发性开角型青光眼(primary open angle glaucoma,POAG)、继发性青光眼(secondary glaucoma,SG)和其他类型青光眼。分析患者的疾病类型、年龄、性别分布等特点以及随时间的变化趋势。主要指标疾病构成比,性别和年龄分布情况。结果共纳入有效病例7569份。PACG为最主要的青光眼类型(5330例),占全部住院病例的70.42%。其次为SG(1517例,20.04%)。POAG和其他类型青光眼患者分别为352例(4.65%)和370例(4.89%)。PACG患者的平均年龄为(66±10)岁,明显高于POAG的(53±15)岁、SG的(57±15)岁和其他类型青光眼的(63±13)岁。PACG中女性患者是男性的2倍(1:2.21),而POAG和SG则主要以男性为主(男:女=1:0.44和1:0.65)。5年间POAG所占比例略有升高(3.37%~5.71%)。患者年龄及性别比例无明显变化。结论 2011-2016年PACG仍为沈阳地区青光眼的主要类型,POAG的住院比例明显低于既往其他城市的报告。

Objective To analyze the epidemiologic characteristics of hospitalized patients with glaucoma in Shenyang and to pro- vide data for the glaucoma health care. Design Retrospective case series. Participants Hospitalized glaucoma patients of 18 years and older in the Fourth People＇s Hospital of Shenyang between Nov.lst, 2011 to Oct. 31st, 2016. Methods 7569 medical files with a dis- charge diagnosis of glaucoma at this hospital were retrospectively reviewed. Patients were divided into primary angle closure glaucoma （PACG）, primary open angle glaucoma （POAG）, secondary glaucoma （SG）, and other types. The constitution, distribution of age and gen- der of different glaucoma types were compared and analyzed. Main Outcome Measures Proportion, age and gender distribution of these glaucoma patients. Results Totally, 7569 cases of glaucoma inpatients were recorded. PACG （n=5330） was the main type （70.42%） followed by SG （20.04%）. POAG （n=352） accounted for 4.65% of the cases, while other types of glaucoma （n=370） accounted for the rest 4.89%. The average age of PACG, POAG, SG and other types of glaucoma were 66±10 years, 53±15 years and 57±15 years and 63±13 years, respectively. PACG showed a female predominant manner （M/F ratio：l：2.21）, while POAG and SG were male predomi- nated （M/F ratio：l：0.44 and 1：0.65, respectively）. During the 5 years, the proportion of POAG showed slow increase （from 3.37% to 5.71%）. Distribution of both the age and gender showed no change. Conclusions PACG is still the most commonly encountered type of glaucoma from 2011 to 2016 in Shenyang. The hospitalized POAG in present study is much lower than other cities reported previously.