雷贝拉唑治疗幽门螺杆菌相关性胃溃疡的效果分析

Effect of rabeprazole in the treatment of Helicobacter pylori associated gastric ulcer

目的:探讨雷贝拉唑治疗幽门螺杆菌(Hp)相关性胃溃疡的效果。方法:收治Hp感染胃溃疡患者90例,分为参照组和试验组。两组均接受阿莫西林、克拉霉素、枸橼酸铋钾治疗。在此基础上,参照组采用奥美拉唑治疗,试验组采用雷贝拉唑治疗,比较两组治疗效果。结果:治疗后,试验组症状评分改善情况、总有效率和血清炎性因子均明显优于参照组(P<0.05)。结论:雷贝拉唑治疗Hp感染胃溃疡的效果显著,安全性高。

Objective：To explore the effect of rabeprazole in the treatment of Helicobacter pylori（Hp） associated gastric ulcer.Methods：90 patients with Helicobacter pylori associated gastric ulcer were selected.They were divided into the reference group and the experimental group.The two groups were treated with amoxicillin,clarithromycin and potassium bismuth citrate.On this basis,the reference group was treated with omeprazole,and the experimental group was treated with rabeprazole.We compared the therapeutic effect of two groups.Results：After treatment,the improvement of symptom score,total effective rate and serum inflammatory factor in the experimental group were obviously superior to those of the reference group（P〈0.05）.Conclusion：The effect of rabeprazole in the treatment of Hp associated gastric ulcer was significant,and the security was high.