屈光不正和眼球生物学参数与糖尿病视网膜病变的相关性

Correlation of DR with ametropia and ocular biological parameters

糖尿病视网膜病变(diabetic retinopathy,DR)是世界范围内引起盲和低视力的主要疾病之一,全身系统疾病(如高血糖、高血压、高血脂等)和眼局部因素均可影响其发生和进展。因此,了解这些危险因素有助于DR预后并对其进行危险分层。研究已经发现近视可能对DR的发生与进展具有保护作用,而研究结果却不尽相同。此外,目前还不清楚近视、眼轴长度(axial length,AL)或者其他屈光成分中哪一种因素是这种保护关系的主要原因。本文对近视、AL、前房深度(anterior chamber depth,ACD)、屈光成分[晶状体及角膜曲率(corneal curvature,CC)]等与DR之间的关系作一全面的综述。

Diabetic retinopathy （ DR） is one of the major diseasesthat causing blindness and low vision in the world. Aseries of systemic （ hyperglycemia, hypertension,hyperlipidemia, etc. ） and ocular factors can effect itsoccurrence and progression. Therefore, understandingthese risk factors may help us to predict the prognosis andstratify the risk. Some studies have found that myopiamay have a protective effect on the occurrence andprogression of DR, but the results are different. Furthermore,it is also unclear which factor in myopia,the axial length,or the other refractive components is themain cause of this protective effect. This paper provides acomprehensive review of the association betweenmyopia, axial length （ AL ）,anterior chamber depth（ ACD） and refractive components （ lens biometry andcorneal curvature） with DR.