普罗帕酮和胺碘酮在阵发性室上性心动过速治疗中应用的疗效

Efficacy of Propafenone and Amiodarone in the Treatment of Paroxysmal Supraventricular Tachycardia

目的:探讨普罗帕酮和胺碘酮在阵发性室上性心动过速治疗中应用的疗效。方法:选取某院2015年6月~2016年4月收治的阵发性室上性心动过速患者124例作为研究对象,随机分为甲组和乙组,各组62例。甲组给予普罗帕酮治疗,乙组给予胺碘酮治疗,记录并对比两组患者血压、心率、转复有效率、转复时间及不良反应出现率。结果:甲组与乙组患者血压、心率、转复有效率未见明显差异(P>0.05);甲组患者转复时间比乙组少,两组对比差异明显(P<0.05);乙组患者不良反应出现率比甲组少,两组对比差异明显(P<0.05)。结论:普罗帕酮和胺碘酮治疗阵发性室上性心动过速疗效均显著,两者对比普罗帕酮转复时间较短、胺碘酮不良反应出现率较低,因此应根据实际状况选择药物。

Objective:To explore the effects of propafenone and amiodarone in the treatment of paroxysmal supraventricular tachycardia.Methods:124 patients with paroxysmal supraventricular tachycardia treated in a hospital from June 2015 and April 2016 were selected as the research object and were randomly divided into group A and group B,with 62 cases in each group.Patients in group A received propafenone for treatment,whereas those in broup B were treated with amiodarone.The blood pressure,heart rate,cardioversion conversion efficiency and time,and the incidence of adverse reactions were compared between the two groups.Results:There was no significant difference between the two groups in blood pressure,heart rate and conversion efficiency(P>0.05).The cardioversion time in group A was shorter than that of group B with significant difference(P<0.05).The incidence of adverse reactions in group B was less than that of Group A,and the difference between the two groups was significant(P <0.05).Conclusion:In treating paroxysmal supraventricular tachycardia,both propafenone and amiodarone are with significant curative effect;The conversion time of propafenone is shorter and the adverse reaction rate of amiodarone is low.Therefore,drugs should be selected according to the actual situation.