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阻塞性睡眠呼吸暂停综合征的表观遗传学研究进展 被引量:2

Epigenetic progress in obstructive sleep apnea syndrome
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摘要 阻塞性睡眠呼吸暂停综合征是一种常见的病因不明的睡眠呼吸障碍性疾病。表观遗传学是指在核苷酸序列不变的条件下,研究基因表达的可遗传变异的一门遗传学分支学科,包括DNA甲基化、组蛋白修饰、染色质重塑、非编码RNA调控等方式。 Obstructive sleep apnea syndrome is a kind of common sleep and respiratory disorder with unknown cause. Epigenetics is a branch of genetics that studies the genetic variation of gene expression under the condition of unchanged nucleotide sequence, including DNA methylation, histone modification, chromatin remodeling, and non coding RNA regulation.
出处 《中国综合临床》 2018年第2期176-179,共4页 Clinical Medicine of China
关键词 阻塞性睡眠呼吸暂停综合征 表观遗传学 DNA甲基化 组蛋白乙酰化 Obstructive sleep apnea syndrome Epigeneties DNA methylation Histone acetylation
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