ROC曲线评价DWI对原发性肝细胞癌RFA术后早期复发病灶的诊断价值

Eevaluation in the Early Recurrence of RFA from Primary Hepatocellular Carcinoma with Diffusion-weighted Imaging: ROC Curve Analysis

目的比较磁共振弥散加权成像(DWI)与多层螺旋CT(MSCT)动态增强扫描对原发性肝癌射频消融(RFA)术后早期复发的检出率,评价DWI对原发性肝癌RFA术后早期复发的诊断价值。方法 71例原发性肝癌CT-RFA术后患者,术后1个月分别行肝脏MR-DWI和MSCT动态增强扫描,采用受试者工作特征曲线(ROC)分析扫描结果。结果 DWI诊断方法的曲线下面积(Az)、灵敏度、特异度和阳性预测值分别为0.914,89.7%,86.0%,83.3%,MSCT动态增强扫描诊断方法的各指标分别为0.671,84.6%,78.0%,75.0%,两种诊断方法比较,差异有显著性(P<0.05)。结论 DWI与MSCT动态增强扫描均可用于原发性肝癌RFA术后复发的早期检出和阳性预测,DWI比MSCT动态增强扫描更具优势。

Objective To compare the detect rate of diffusion-weighted magnetic resonance imaging（ DWI）and dynamic contrast-enhanced spiral CT scan（ MSCT） in the detection of early palindromia of RFA from primary hepatocellular carcinoma,and to evaluate the early diagnosis of DWI for the early recurrence of RFA. Methods Seventy-one cases of primary hepatocellular carcinoma after RFA surgery were treated by liver scan and magnetic resonance DWI dynamic contrast-enhanced MSCT scan. The results were analyzed by receiver operating characteristic curve（ ROC）. Results Results of diagnostic methods DWI area under the curve（ Az）,sensitivity,specificity and positive predictive values were 0. 914,89. 7%,86. 0% and 83. 3%,MSCT diagnosis were 0. 671,84. 6%,78. 0%,75. 0%,two sets of results were statistically significant（ P〈0. 05）. Conclusion For early detection of palindromia and positive predictive of primary hepatocellular carcinoma after RFA,DWI has much more advantages.