脑-硬脑膜-颞浅动脉血管融通术治疗缺血性烟雾病的临床效果观察

Observe the Clinical Effect of EDAS in the Treatment of Ischemic Moyamoya Disease

目的探究脑-硬脑膜-颞浅动脉血管融通术治疗缺血性烟雾病的临床应用效果。方法选取2016年2月~2017年5月收治86例缺血性烟雾病患者作为研究对象,根据患者就诊时间分为研究组和对照组,每组43例。研究在给予脑-硬脑膜-颞浅动脉血管融通术治疗,对照组仅给予抗血小板凝集剂联合钙通道阻滞剂治疗,观察两组患者血流动力学指数,并进行统计学分析。结果研究组治疗后颈内动脉、颈外动脉分支供血血管血流量优于对照组,组间对比存在统计学意义(P<0.05)。结论脑硬脑膜颞浅动脉血管融通术相对于药物治疗可有效患者患者颈内、颈外血管压力和血流量,保护脑组织功能,减缓疾病进展。

Objective To explore the clinical application of EDAS （ encephalo - duro - arterio synangiosis） in pa- tients with ischemie moyamoya disease. Methods 86 patients with ischemic moyamoya disease treated from February 2016 to May 2017 in our hospital were selected and divided into two groups according to the registration time, 43 cases each group. The study group took the EDAS while the control group took the antiplatelet aggregation agents and calcium channel blockers. The hemodynamics index was analyzed. Results After treatment, the blood flow volume of the inter- na] carotid artery and external carotid artery branches for study group were significantly better than control group （ P 〈 0. 05 ）. Conclusions The EDAS can efficiently improve the vascular pressure and blood flow volume of the internal ca- rotid and external carotid artery, protect the brain tissue and slow down the disease progression.