摘要
An atom economical highly efficient method has been developed for the synthesis of quinoline and 1,2,3,4-tetra- hydroquinoline derivatives from o-nitrotoluenes bearing electron-withdrawing groups and olefins （acrylic esters, acrylonitriles, and methyl acrylates） via a base-catalyzed [2＋4] cycloaddition. This simple, rapid, and environment- friendly method provides a practical pathway for the synthesis of quinoline and 1,2,3,4-tetrahydroquinoline derivatives. The starting materials are readily available and 37 products were obtained in good to excellent yields.
An atom economical highly efficient method has been developed for the synthesis of quinoline and 1,2,3,4-tetra- hydroquinoline derivatives from o-nitrotoluenes bearing electron-withdrawing groups and olefins （acrylic esters, acrylonitriles, and methyl acrylates） via a base-catalyzed [2＋4] cycloaddition. This simple, rapid, and environment- friendly method provides a practical pathway for the synthesis of quinoline and 1,2,3,4-tetrahydroquinoline derivatives. The starting materials are readily available and 37 products were obtained in good to excellent yields.
