摘要
目的:探讨QTc延长并发尖端扭转型室速的原因,为临床用药的安全性提供参考。方法:临床药师参与1例胺碘酮合用莫西沙星致QTc间期延长并发尖端扭转型室速的治疗,分析不良反应发生的原因及处理方法。结果:此次不良反应可能与胺碘酮和莫西沙星有关,该患者危险因素较多,临床用药时应加强用药安全的监督。结论:临床使用胺碘酮联用莫西沙星时,临床药师应掌握药物相互作用,加强药学监护,提高用药安全性。
Objective: To investigate the causes of QTc interval prolongation complicated by torsade de pointes, and to provide reference for drug safety. Methods: Clinical pharmacists participated in the treatment and causes analysis for a patient with QTc interval prolongation complicated by torsade de pointes induced by amiodarone and moxifloxacin. Results: The adverse effect might be related to amiodarone and moxifloxacin, the clinical drug monitoring should be strengthened on this patient with many risk factors. Conclusion:Drug-drug interactions should be recognized by clinical pharmacists as amiodarone combined with moxifloxacin. The pharmaceutical care should be strengthened for improving drug safety.
出处
《临床药物治疗杂志》
2017年第11期77-79,83,共4页
Clinical Medication Journal