2013―2015年我国7城市105家样本医院脂肪乳剂使用分析

Analysis of fat emulsion injection in 105 sample hospitals among seven cities in China during 2013―2015

目的:分析我国7城市105家医院2013―2015年肠外营养脂肪乳剂用药情况现状,并做出客观评估。方法:对参与《医院处方分析》课题组研究的我国7城市105家医院肠外营养脂肪乳剂用药情况进行抽样统计,并计算其按基质分类使用情况、进口/国产使用金额增长情况、门、急诊病房使用情况及科室分布、患者年龄分布、用药频度(DDDs)及其年平均增长率、日均费用(DDC)及其年平均增长率等。结果:第二代脂肪乳剂使用量最大,临床信任度高;脂肪乳剂使用以进口为主;门、急诊病房脂肪乳剂使用结构上有较大差异;使用量科室排名位于前3位的分别是肿瘤内科、消化内科及普通外科;患者使用年龄集中分布在中老年人;结构脂肪乳剂及鱼油脂肪乳剂DDDs逐年增大,长链脂肪乳剂则逐年下降;DDC值变化不大。结论:临床使用脂肪乳剂总体情况合理,但仍有需要改进的地方。

Objective： To study and analyze the status of parenteral fat emulsion in 105 hospitals among seven cities m China from 2013 to 2015, and to offer an objective assessment. Methods： The samples of parenteral fat emulsion in 105 hospitals among seven cities in China were sampled and calculated the ratio of different matrix fat emulsion, the sales growth of domestic products or imported products, distinctions between outpatient, emergency and ward on the use of emulsion, departmental distribution, patient age distribution, defined daily doses（DDDs） and annual average growth rate, defined daily cost （DDC） and annual average growth rate. Results： The second generation fat emulsion used the largest; mainly use imported fat emulsion; outpatient, emergency and ward fat emulsion use structurc is quite different; usage department ranking in the top three are the medicine oncology, digestive system department and general surgery; the age of patients used fat emulsion concentrated was the elderly; the DDDs of structured triglyeeride and fish oil liquid emulsion increased year by year, long-chain triglyceride decreased year by year; DDC hold steady in this three years. Conclusion： The overall usage of tat emulsion is reasonable, but there is still room for imorovement.