慢性颈动脉粥样硬化闭塞治疗的研究进展

The treatment for chronic atherosclerotic occlusion of carotid:research progress

慢性颈动脉粥样硬化闭塞会导致脑血流低灌注而增加卒中风险。无症状患者首选药物治疗,对于反复出现神经症状的患者可选择手术治疗。颅外-颅内动脉旁路术(extracranial-intracranial artery bypass,EIAB)治疗效果不优于药物治疗。颈动脉内膜剥脱术(carotid endarterectomy,CEA)、颈动脉支架成形术(carotidartery stent,CAS)手术风险高、成功率低,治疗效果尚待验证,故术前应严格筛选患者、把握适应证。本文就目前对于慢性颈动脉闭塞的治疗现状作一综述。

Chronic atherosclerotic occlusion of carotid can lead to low cerebral blood flow and increase the risk of stroke.Drug therapy is the first choice for asymptomatic patients,while the patients with recurrent neurological symptoms may need surgical treatment.Extracranial-intracranial artery bypass（EIAB）is not better than medicine treatment.The operation risks of carotid endarterectomy（CEA）and carotidartery stent（CAS）are high with low success rate and the therapeutic effects remain to be verified.Therefore,the surgical indications should be strictly controlled.In this paper,the current status of treatment for chronic carotid artery occlusion was reviewed.