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血清25-羟维生素D_3水平与总抗氧化能力及颈动脉粥样硬化的关联性研究 被引量:3

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摘要 目的研究血清25-羟维生素D_3[25-(OH)D_3]水平与总抗氧化能力(T-AOC)及颈动脉粥样硬化的关联性。方法颈动脉粥样硬化患者200例为观察组,选同期健康体检者200例为对照组。对比两组血清25-(OH)D_3及T-AOC水平。观察组行彩色多普勒超声检查,分析不同颈动脉狭窄程度、颈动脉内膜中层厚度(IMT)与25-(OH)D_3及T-AOC水平的相关性。结果观察组血清25-(OH)D_3及T-AOC水平均低于对照组(P<0.05);经单因素方差分析,不同颈动脉狭窄程度及IMT患者血清25-(OH)D_3及T-AOC水平差异有统计学意义(P<0.05);颈动脉狭窄程度及颈动脉IMT越高,血清25-(OH)D_3、T-AOC水平越低(P<0.05);观察组血清25-(OH)D_3与T-AOC呈正相关(P<0.05)。结论颈动脉粥样硬化与血清25-(OH)D_3及T-AOC水平有明显相关性。
出处 《中国地方病防治》 北大核心 2017年第9期1051-1052,共2页 Chinese Journal of Control of Endemic Diseases
基金 国家高技术研究发展计划"863"计划(编号2014AA022304)
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