银杏叶提取物治疗轻中度非增生期糖尿病视网膜病变的临床效果观察

Clinical effect of the extract of Ginkgo biloba （ Ginkgo biloba tincture） in the treatment of mild to moderate non proliferative diabetic retinopathy

目的 探讨银杏叶提取物对轻中度非增生期糖尿病视网膜病变的临床疗效.方法 选取200例轻中度非增生期糖尿病视网膜病变患者为研究对象,采用随机数字表法分为两组,每组100例,对照组患者给予阿司匹林肠溶片治疗,观察组患者给予阿司匹林肠溶片加银杏叶提取物治疗,分析两组患者的效果.结果 观察组临床治疗总有效率（83.52％）与对照组的（60.67％）相比较,组间差异有统计学意义（χ^2=12.976,P〈0.05）;观察组治疗后的视力水平、视野平均缺损分别为（4.84±0.10）、（2.52±0.13）dB,与对照组的（4.74±0.18）、（3.09±0.32）dB相比较,组间差异有统计学意义（t=0.535、22.228,均P〈0.05）.结论对轻中度非增生期糖尿病视网膜病变患者应用银杏叶提取物治疗的效果较好,可明显提高患者的视力水平,减少视野缺损.

Objective To investigate and analyze the clinical effect of Ginkgo biloba extract on mild to mod-erate non proliferative diabetic retinopathy .Methods 200 patients with mild to moderate non proliferative diabetic retinopathy were randomly divided into two groups ,100 cases in each group .The control group was treated with aspirin enteric-coated tablets .The observation group was given aspirin enteric -coated tablets and Ginkgo biloba extract . The clinical effect of the two groups was analyzed .Results The total effective rate of the observation group （83.52%） was significantly higher than that of control group （60.67%） （χ^2 =12.976,P〈0.05）.After treatment, the visual acuity level,mean defect of visual field in the observation group were （4.84 ±0.10）,（2.52 ±0.13）dB, respectively,which in the control group were （4.74 ±0.18）,（3.09 ±0.32）dB,respectively,the differences between the two groups were statistically significant （t=0.535,22.228,all P〈0.05）.Conclusion Ginkgo biloba extract has good effect in the treatment of patients with mild to moderate non proliferative diabetic retinopathy ,it can signifi-cantly improve the patients＇visual acuity ,visual field defect reduction .