4Jason RN, Kyle MJ, Raphael AN, et al. Cox -2 inactivates Smad signaling and enhances EMT stimulated by TGF - b through a PGE2 - dependent mechanisms [J]. Carcinogene- sis, 2008, 29 ( 11 ) : 2227.
5Hanazono K, Natsugoe S, Stein HI, eta. Distribution of p53 mutations in esophageal and gastric carcinomas and the rela- tionship with p53 expression [J]. Oneol Rep, 2006,15 (4) : 821.
6Alazzouzi H, Alllopuro P, Salovaara R, et ai. SMAIM as a prognostic marker in colorectal cancer[ J]. Clin Cancer Res, 2005, 11 (7) : 2606.
7Zhao S, Ammanamanchi S, Brattain M, et al. Smad4 -de- pendent TGF -beta signaling suppresses RON receptor tyro- sine kinase - dependent motility and invasion of pancreatic cancer cells[ J ]. J Biol Chem, 2008, 283 ( 17 ) : 11293.
8Bonaterra GA, Kelber O, Weiser D, et al. In vitro anti - pro- liferative effects of the willow bark extract STW 33 - I [ J ]. Arzneimittelforschung, 2010, 60(6): 330.
9Lin KY, Fang CL, Uen YH, et al. Overexpression of protein kinase Calpha mRNA may be an independent prognostic mark- er for gastric carcinoma [J] J Surg Oncol, 2008, 97 ( 6 ) : 538.
10Hirokazu Okano, Hisashi Shinohara, Akiko Miyamoto et al. Concomitant Overexpression of Cyclooxygenase - 2 in HER - 2 - Positive on Smad4 - Reduced Human Gastric Carcinomas Is Associated with a Poor Patient Outcome [ J ]. Clinical Cancer Research, 2004,10 : 6938.
