人参皂苷Rd分析方法、药物代谢动力学及剂型研究进展

The Research Progress of Analytic Methods,Pharmacokinetics and Dosage Form of Ginsenoside Rd

人参皂苷Rd是人参主要活性成分之一,具有广泛的药理活性,可改善心脑血管系统、保护神经系统、治疗溃疡性结肠炎、抑制肿瘤细胞生长、延缓衰老等功能。本文参考了近年来国内、外有关人参皂苷Rd研究的文献,对其分析方法、药物代谢动力学特征及剂型情况进行综述,为人参皂苷Rd的临床应用及进一步开发与利用提供理论参考。

Ginsenoside Rd, which has wide pharmacological effects, is one of the key active component of ginseng.Studies show that Ginsenoside Rd could improve cardiovascular system, protect nervous system, treat ulcerative colitis, inhibit angiogenesis and tumor cells, delay senilly and so on. This text summarized the analytic methods, pharmacokinetics and dosage form ofGinsenoside Rd by re- searching relative literature at home and abroad in recent years, which provides a theoretical reference for the clinical application, further development and utilization of Ginsenoside Rd.