摘要
睡眠嗜血杆菌(睡眠嗜组织菌)是引起牛多系统疾病的病原,是一种革兰氏阴性多形态棒状细菌。除引起牛发生败血症、血栓性脑膜炎、多发性关节炎、血管炎、流产和不育外,还可感染绵羊、北美野牛和大角羊。睡眠嗜血杆菌的脂寡糖和免疫球蛋白结合蛋白是主要的毒力因子,综述了睡眠嗜血杆菌的主要致病毒素及宿主对其的免疫反应。
Haemophilus sonmus ('Histophilus somni' ) was an opportunistic pathogen associated with multi-system disease in cattle and was a polymorphic gram-negative coryneform bacterium.h not only caused cattle sepsis, thrombotic meningitis, multiple arthritis, vasculifis,abortion and infertility,but also led to sheep,bison and big bighorn sheep disease.The lipopolysaccharide and immunoglobulin-binding proteins of Haemophilus influenzae were the main virulence factors.This paper reviewed the main pathogenic toxins of Haemophilus influenzae and the host immune response.
出处
《黑龙江八一农垦大学学报》
2018年第1期17-20,共4页
journal of heilongjiang bayi agricultural university
关键词
睡眠嗜血杆菌
毒力因子
进展
Haemophilus somnus
virulence factors
progress