EB病毒性肝炎40例临床分析

Clinical analysis of 40 patients with EB viral hepatitis

目的探讨EB病毒性肝炎的临床表现、疗效及预后。方法回顾性分析40例住院EB病毒性肝炎患者的临床资料,将患者分为单一EB病毒性肝炎组18例和EB病毒性肝炎合并其他原因肝损害组22例,总结2组的临床特点。结果EB病毒性肝炎主要临床表现为乏力、食欲下降、黄疸、肝脾肿大,及不同程度损害。合并肝炎组总胆红素(TBIL)、谷丙转氨酶(ALT)及谷草转氨酶(AST)水平显著高于单一EB病毒性肝炎组(P<0.05)。结论 EB病毒感染是肝功能损害原因之一。

Objective To investigate the clinical manifestation, curative effect and progno- sis of patients with EB viral hepatitis. Methods Clinical data of 40 hospitalized patients with EB vi- ral hepatitis was retrospectively analyzed. The patients were divided into single EB viral hepatitis group （n = 18 ） and EB viral hepatitis complicated with other liver damage group （n = 22）. The clin- ical characteristics were summarized. Results The main clinical manifestations of patients with EB viral hepatitis were fatigue, anorexia, jaundice, hepatosplenomegaly, and different degrees of damage. Levels of serum total bilirubin （TBIL）, alanine aminotransferase （ALT） and aspartate amin- otransferase （AST） in EB viral hepatitis complicated with other liver damage group were significantly higher than those in single EB viral hepatitis group （P 〈 0.05 ）. Conclusion EB virus infection is one of the causes of liver function damage.