白头婆的化学成分及药理作用研究进展

Advances on the chemical constituents and pharmacological effects of Eupatorium japonicum

白头婆为菊科泽兰属植物,在韩国是一种茶饮,在我国是少数民族常用的草药,土家族俗称"仙草"。本文总结了近40年来白头婆的化学成分及药理作用研究情况,白头婆中共分离鉴定了6个化学成分(苯丙素类、倍半萜类各3个),药理学研究集中于韩国、日本和中国,具有抑制昆虫发育、抗肿瘤、抗炎、抗骨质疏松及抗菌等药理作用。白头婆的化学成分及药理作用研究有待进一步开展。

Eupatorium japonicum,belongs to the genus Eupatorium of Asteraceae,which has been consumed as a tea in South Korea and used as medicines in Chinese minority groups（ called ＂Xiancao＂in Tujia）. This paper summarized the recent 40 years＇ studies on chemical constituents and pharmacological effects of E. japonicum.In total,only 6 chemical constituents（ 3 phenylpropanoids and 3 sesquiterpenes） have been separated and identified. Pharmacological studies were mostly in South Korea,Japan and China. It was reported that E. Japonicumhas inhibitory effects against insect development,and has anti-tumor,anti-inflammatory,anti-osteoporotic and antibacterial pharmacological effects. The chemical constituents and pharmacological effects of E. Japonicum need to be further studied.