围绝经期失眠症患者中医体质与中医证型相关性研究

Study on the Correlation between TCM Constitution and TCM Syndromes in Patients with Insomnia of Perimenopausal Women

目的研究围绝经期失眠症患者中医体质与证型的关系,为临床防治围绝经期失眠症提供新的思路与方法。方法以200例围绝经期失眠症患者为观察组,200例无临床症状者围绝经期女性为对照组。以《中医体质分类与判定表》对入选病例进行中医体质分类,运用logistic回归分析探讨对围绝经期失眠症发病有影响的中医体质类型,运用对应分析探讨围绝经期失眠症患者中医体质类型与中医证型之间的关系。结果观察组与对照组中医体质构成比不同,平和质、痰湿质、血瘀质和气郁质在2组间的分布差别显著(P<0.01);logistic回归分析提示,影响围绝经期失眠症发病的体质有平和质、痰湿质、血瘀质和气郁质;对应分析提示,痰湿质与痰热扰心证存在对应关系,气郁质与肝郁化火证存在对应关系,阳虚质与心肾不交证存在对应关系,气虚质与心脾两虚证存在对应关系。结论围绝经期失眠症与中医体质类型有密切的关系,痰湿质、血瘀质和气郁质是围绝经期失眠症的易感体质,平和质是保护体质;围绝经期失眠症患者中医体质类型与中医证型存在对应关系。

Objective To study the correlation relationship between TCM constitution and TCM syndromes in patients with insomnia,and to provide new ideas and methods for clinical prevention and treatment of perimenopausal insomnia. Methods 200 cases of perimenopausal insomnia patients were selected as the observation group. 200 cases of healthy women were selected as the control group. The classification of traditional Chinese medicine was classified according to the classification and determination of constitution in TCM. Logistic regression analysis was used to explore the types of TCM constitution that had an effect on perimenopausal insomnia.The relationship between TCM constitution and TCM syndromes was discussed. Results The composition ratio between the observation group and the control group was different. The distribution of gentler, phlegm-dampness, blood stasis and qi stagnation were significant in the two groups（P0.01）. Logistic regression analysis affected the onset of perimenopausal insomnia with a moderate constitution,gentler, phlegm-dampness, blood stasis and qi stagnation. Corresponding analysis tips indicted there was a correspondence between phlegm-dampness and phlegm heat disturbing, qi stagnation and syndrome of liver depression transforming into fire, yang deficiency and syndrome of disharmony between heart and kidney, qi deficiency and syndrome of deficiency of both heart and spleen was existed.Conclusion Perimenopausal insomnia is closely related to the type of TCM constitution. Phlegm-dampness, blood stasis and qi stagnation were susceptible to perimenopausal insomnia. The gentler in constitution is the protection one. The correlation relationship between TCM constitution type and TCM syndromes in patients with perimenopausal insomnia was existed.