生化汤联合甲氨喋呤在早期异位妊娠治疗中的临床研究

Clinical Study of Biochemical Decoction Combined with Methotrexate in the Treatment of Ectopic Pregnancy

目的观察生化汤联合甲氨喋呤在早期异位妊娠治疗中的临床研究。方法选择2013年1月—2017年6月在我院接受治疗的200例异位妊娠患者为研究对象,将符合标准患者随机分为对照组和观察组,每组100例。对照组采用甲氨喋呤治疗,观察组在对照组的基础上加服中药生化汤展开疾病治疗,最终就2组异位妊娠患者治疗结果展开对比。结果同对照组异位妊娠患者治疗总有效率比较,观察组异位妊娠患者显著性提高(P<0.05);同对照组异位妊娠患者治疗后阴道流血时间、包块消失时间、血β-HCG恢复正常时间以及月经恢复时间展开对比,观察组异位妊娠患者显著改善(P<0.05);同对照组不良反应发生率对比,观察组异位妊娠患者显著性降低(P<0.05)。结论生化汤联合甲氨喋呤治疗异位妊娠能够充分发挥中医学的优势,可以使得患者的血β-HCG水平以及包块消失时间显著缩短,使临床症状显著改善,治疗安全性显著,对患者的早期康复具有积极意义,也为异位妊娠这一妇科常见多发病寻找新的中医药治疗方法拓宽了思路。

Objective To observe the clinical study of biochemica l decoction combined with methotrexate in the treatment of early ectopic pregnancy. Methods Two hundred and eighteen patients with ectopic pregnancy treated in our hospital from January 2013 to June 2017 were selected as the study subjects, and the patients who met the criteria were randomly divided into control group and observation group, with 100 cases in each group. The control group received methotrexate treatment. The observation group received biochemical decoction on the basis of the control group. Finally, the two groups of ectopic pregnancy treatment results were compared.Results Comparing with the control group, the total effective rate of the observation group was significantly improved（ P 0.05）.The ectopic pregnancy vaginal bleeding time, disappearance of mass, blood β-HCG recovery time and menstrual recovery time of the observation group ectopic pregnancy patients achieved significant improvement（ P 0.05）. Compared with the incidence of adverse reactions in the control group, the observation group ectopic pregnancy patients were significantly reduced（ P 0.05）. Conclusion Biochemical decoction combined with methotrexate in the treatment of early ectopic pregnancy can give full play to the advantage of the traditional Chinese medicine, can make β-HCG and mass disappearance time significantly shortened, which significantly improve the clinical symptoms, and has significant safety, is of positive significance to the early rehabilitation of patients, also broadens the way to find new traditional Chinese medicine treatment for ectopic pregnancy, which is a common gynecological disease.