利培酮结合音乐治疗对精神分裂症患者的疗效

Clinical efficacy of risperidone combined with music therapy in patients with schizophrenia

目的探究利培酮结合音乐治疗对精神分裂症患者的临床效果。方法选择2014年11月~2016年01月在我院确诊住院的精神分裂症患者共83例,随机分为2组,其中药物治疗组有40例患者,予以利培酮方案系统治疗;综合治疗组有43例患者,予以利培酮和音乐联合治疗方案系统治疗。分别于治疗前、治疗后1个月、治疗后2个月评估两组患者的简明精神病评定量表(BPRS),并根据治疗前后阳性症状与阴性症状量表(PANSS)的减分情况评定两组治疗疗效。结果药物治疗组入选对象总有效率(80.00%)明显低于综合治疗组(95.35%),差异有统计学意义(P<0.05);两组患者治疗前BPRS评分组间无明显差异(P>0.05),治疗1个月及2个月后,两组患者的BPRS评分均降低,且治疗后两组评估的BPRS评分综合治疗组均明显低于药物治疗组,差异有统计学意义(P<0.05)。结论与单一利培酮的药物治疗,利培酮和音乐联合治疗方案能更有效改善精神分裂症患者地临床症状及预后情况,在精神科有推广的意义及价值。

Objective To explore the clinical efficacy of risperidone combined with music therapy in patients with schizophrenia. Methods From November 2014 to January 2016, a total of 83 cases patients with schizophreniahospitalized in our hospital were selected for this research, and then divided into 2 groups randomly： the medical treatment group with 40 patients were given risperidone treatment; while the comprehensive treatment group with 43 patients were given risperidone combined with implementation of music therapy. Before as well as 1 month and 2 months after treatment, Brief Psychiatric Rating Scale （ BPRS ） were evaluated and compared between the two groups, and the score reduction of Positive and Negative Syndrome Scales （ PANSS ） were used to evaluate the treatment efficacy of the two groups. Results The total efficiency of the medical treatment group （ 80 % ） was significantly lower than that of the comprehensive treatment group （95.35 % ）, the difference was statistically significant （P〈0.05）; the BPRS scores showed no obvious difference between the two groups of patients before treatment （P〉0.05）; 1 months and 2 months later, the BPRS scores of two groups were both decreased, and BPRS scores of comprehensive treatment group were significantly lower than those of the treatment group, the differences were statistically significant （P 〈 0.05 ） . Conclusion Compared with risperidone only, risperidone and music combined treatment can be more effectively to improve the prognosis and clinical symptoms of patients with schizophrenia, . Thus, it＇ s worthy of thepromotion significance and value in psychiatric department..