上海市女性脸部和手部的皮肤特征及与年龄相关性

Differences of skin characteristics between face and hand and its correlation with age in female from Shanghai

目的比较上海市女性脸部和手部皮肤的基础状况。方法招募139名23～46岁上海市女性，采用无创性皮肤测试仪器测试脸颊、额头、手背、手掌的皮肤水合度、pH值、经皮水分丢失（transepidermal water loss，TEWL）和弹性。结果水合度由高到低依次为额头、脸颊、手背和手掌，4个部位间差异显著。pH值脸颊最高，额头最低，手掌和手背之间差异无统计学意义。TEWL值手掌最高，脸颊最低，额头和手背之间在不同年龄组中差异不一致。皮肤弹性R2值脸颊最高，额头、手背、手掌间差异不显著，R2和R7值在低年龄和高年龄组出现分化，低年龄组脸颊最高、手掌最低，高年龄组脸颊和额头、手掌和手背开始趋近。除了脸颊和手背的弹性参数，其他部位参数均在不同年龄组间无差异，与年龄没有明显相关性。结论脸颊的皮肤屏障和弹性最好，pH值最高，弹性随年龄增长而下降；额头水合度最高，pH值最低；手背的弹性参数与额头比较接近，弹性也随年龄增长而下降；手掌的TEWL最高，水合度最低，弹性R2较高，但R5和R7最低。

Objective To estimate the differences between face and hand skin and age correla tion in females aged 23-46 years living in Shanghai. Methods 139 women aged 23-46 years from Shanghai attended this program. The water content, pH, TEWL and elasticity of cheek, forehead, hand back of and palm were evaluated by non-invasive skin test instruments. Results The skin water content of these four parts from high to low were forehead, cheek, hand back and palm, and they were different from each other significantly. The pH of cheek was the highest, and forehead was the lowest; there was no significant difference between hand back and palm. TEWL of palm was the high- est, and cheek was the lowest; the difference between forehead and hand back was inconsistent in dif- ferent age groups. The elasticity of cheek was the highest. There was no significant difference in R 2 between forehead, hand back and cheek. The condition of R~ and R7 was different between younger group and older group. In young group the cheek was the highest, and palm was the lowest. In older group, cheek and forehead, palm and hand back began to converge. In addition to the elasticity of cheek and hand back, other parameters of other parts had no significantly difference between different age groups, and also had no significant correlation. Conclusions The cheek has the best skin barrier, elasticity and the highest pH, and the elasticity of cheek decreases with age. The forehead has the highest water content and lowest pH, TEWL and the elasticity of hand back are close to the forehead, and the elasticity of hand back decreases with age. The palm has the highest TEWL and lowest water content. Its total recovery amount in the elastic curve is higher, but the elastic ratio in the recovery is the lowest.