摘要
中药配伍作为现代复方药物的重要线索和参考,成为具有中国特色和中药特点的固定剂量组合药的一种创新研发模式。但是中药复方由于成分复杂、数量巨大、结构多样,药效物质的寻找和确定是难中之难。要解决这一难题,需要思路、方法和技术创新。
As an important clue and reference for modern compound medicine, Chinese medicine compatibility has become an innovative research and development mode of fixed dose combination with Chinese characteristics and traditional Chinese medicine(TCM) characteristics. However, it is difficult to find and determine the effective substances because of the complex composition, the huge amount and the structure diversity. In order to solve these problems,innovative ideas, methods and techniques are needed.
出处
《世界科学技术-中医药现代化》
CSCD
2017年第11期1765-1767,共3页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委重点项目:基于体内过程的两种知母药对配伍机制研究(81030065)
负责人:黄成钢
国家科学技术部国家"重大新药创制"科技重大专项课题:治疗2型糖尿病中药复方RG02组分配伍新药临床前研究(2009ZX09102-121)
负责人:黄成钢
关键词
中药配伍
中药复方
药效物质基础
创新药物研发
Compatibility of traditional Chinese medicine, Chinese medicine compound, pharmacophore basis, research and development of innovative drugs