摘要
目的分析老年高血压住院患者的临床特点与治疗效果。方法将2015年9月-2016年9月于医院接受治疗的老年高血压患者100例作为研究对象,根据治疗方法的不同将其分为试验组和对照组各50例。其中试验组采用氯沙坦联合氢氯噻嗪治疗,对照组采用氢氯噻嗪治疗。分析2组患者的临床特点,并对2组患者的治疗效果进行比较。观察2组的舒张压、收缩压及平均动脉压。结果 100例患者中1级高血压13例,2级高血压28例,3级高血压18例,单纯性收缩期高血压41例,其中合并心力衰竭6例,脑梗死7例,糖尿病9例,冠心病4例,肾功能不全4例。患者的临床表现较多,其中失眠、头痛、头晕、耳鸣是最常见的症状,39例患者有以上症状;18例患者以胸闷、心慌、心前区隐痛等症状为主;12例患者以心尖区Ⅱ级以上收缩期杂音为主;12例患者以左心室肥厚为主,10例患者以肢体麻木为主,9例患者以偏瘫为主要表现。试验组患者的治疗总有效率为96.00%高于对照组的76.00%,差异有统计学意义(P<0.05)。试验组治疗后舒张压、收缩压及平均动脉压明显低于对照组,差异均有统计学意义(P<0.05)。结论老年高血压患者的临床特点较为复杂,并且以收缩压上升为主要表现,采用氯沙坦联合氢氯噻嗪治疗的效果较好,具有较高临床价值。
Objective To study the clinical characteristics and treatment effect of blood pressure in elderly patients with hypertension. Methods 100 elderly hypertensive patients receiving treatment in the hospital from September 2015 to September 2016 were divided into experimental group and control group,each of 50 cases. The patients in experimental group were treated with losartan and hydrochlorothiazide,and control group was treated with hydrochlorothiazide. The clinical features of two groups were analyzed and the therapeutic effects of two groups were compared. The diastolic blood pressure,systolic blood pressure and mean arterial pressure were observed in two groups. Results Among 100 patients Grade 1 hypertension in 13 cases,Grade 2 hypertension in 28 cases,Grade 3 hypertension in 18 cases,simple systolic hypertension in 41 cases,including 6 cases of heart failure,cerebral infarction in 7 cases,diabetes mellitus in 9 cases,coronary heart disease in 4 cases,4 cases of renal insufficiency. The clinical manifestations of patients was more,among them the insomnia,headache,dizziness,tinnitus were the most common symptoms,39 patients with the above symptoms; 18 patients with chest tightness,palpitation,anterior area pain and other symptoms mainly; 12 patients in the apical area Ⅱ above the level of systolic murmur; 12 patients mainly left ventricular hypertrophy,10 patients were mainly numbness,9 patients with hemiplegia as the main performance. The total effective rate of experimental group was 96. 00% higher than 76. 00% of control group,the difference was statistically significant( P 0. 05). The diastolic blood pressure,systolic blood pressure and mean arterial pressure in experimental group were significantly lower than those in control group after treatment,the differences were statistically significant( P 0. 05). Conclusion The clinical characteristics of elderly hypertensive patients are complex,and the rise of systolic blood pressure is the main manifestation. The effect of losartan and hydrochlorothiazide is better,and it has higher clinical value.
出处
《临床合理用药杂志》
2018年第4期15-16,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
老年高血压
临床特点
治疗效果
Elderly hypertension
Clinical characteristics
Treatment effect