封闭负压引流技术联合糜蛋白酶治疗下颌骨创伤后骨髓炎的临床应用

Clinical application of vacuum sealing drainage combined with chymotrypsin in the treatment of post-traumatic mandibular osteomyelitis

下颌骨创伤后骨髓炎的治疗以手术和药物联合治疗为主。本文介绍采用封闭负压引流技术（vacuum sealing drainage，VSD）为主的病灶清理术，术后同时行4000U糜蛋白酶＋500ml生理盐水持续冲洗的治疗方法。初步探讨VSD联合糜蛋白酶在下颌骨创伤后骨髓炎病例中的应用效果，证实其对保证引流、控制感染、保留内固定有良好作用并可为骨折愈合创造良好环境。以期为下颌骨创伤后骨髓炎的有效治疗提供更简便有效的新方法。

This article introduces the combined application of vacuum sealing drainage （VSD） and chymotrypsin in the treatment of post-operative mandibular osteomyelitis. The lesion was washed by chymotrypsin （4000U） and saline （500 ml）. VSD is effective in the treatment of traumatic mandibular osteomyelitis. This study investigates the effect of VSD combined with chymotrypsin in the treatment of patients with osteomyelitis after mandibular trauma. It is proved that it has a good effect in ensuring drainage, controlling infection and retaining internal fixation, and can create a good environment for fracture healing.