隆突性皮肤纤维肉瘤3例报告并文献回顾

Dermatofibrosarcoma protuberans:three cases report and literature review

目的报告3例隆突性皮肤纤维肉瘤的发病情况,同时复习文献,探讨该病的临床及组织病理学特点,以提高其诊疗水平。方法分析3例隆突性皮肤纤维肉瘤的临床资料,并进行文献复习,总结本病的临床表现及组织病理学特点。结果根据皮损表现及组织病理学检查,最后诊断为隆突性皮肤纤维肉瘤。3例患者均行皮损扩大切除术,随诊无复发。结论隆突性皮肤纤维肉瘤临床少见,结合临床表现和组织病理以及免疫组化染色结果可以确诊,治疗可以手术扩大切除。

Objective To report three cases of dermatofibrosarcoma protuberans and review the literatures, so as to improve the level of diagnosis and treatment of the disease. Methods The medical records of three cases of dermatofibrosarcoma protuberans were analyzed and the relevant literatures were reviewed, furtherly the clinical and histopathological features of the disease were summarized. Results All the 3 patients were diagnosed as dermatofibrosarcoma protuberans based on the clinical and histopathology features, and underwent extended surgical treatment. The patients had been followed up for 3 months without recurrence. Conclusion Dermatofibrosarcoma protuberans is an infrequent dermatosis, and the diagnosis of the disease is based on the clinical manifestations, histopathology and immunohistochemistry analysis. Surgical resection is an effective therapy for the disease.