反射式共聚焦显微镜对不典型银屑病的辅助诊断:附3例病例分析

Auxiliary diagnosis of atypical psoriasis by reflection confocal microscopy:three cases analysis

目的观察反射式共聚焦显微镜对不典型银屑病的诊断意义。方法将3例皮损不典型、可疑银屑病的皮损进行反射式共聚焦激光扫描显微镜(reflectance confocal microscopy,RCM)扫描,同时行组织病理检查。结果 3例患者的RCM图像均具有Munro微脓肿及银屑病样增生模式,与组织病理改变相互对应,符合寻常性银屑病的改变。结论反射式共聚焦激光扫描显微镜对不典型银屑病的诊断具有辅助诊断意义,给疾病的诊断与鉴别提供新的方法和思路。

Objective To evaluate the application of reflectance confocal microscopy in auxiliary diagnosis of atypical psoriasis. Methods Reflex confocal laser scanning microscope（reflectance confocal microscopy, RCM） and histopathological examination were carried out for three cases with atypical psoriasis lesions. Results The RCM images of these three cases had Munro micro abscess and psoriasis-like hyperplasia model, which corresponded to the pathological changes of psoriasis vulgaris and accorded with the changes of psoriasis vulgaris. Conclusion Reflection confocal laser scanning microscope may be useful in auxiliary diagnosis of atypical psoriasis, which provides new methods and new ideas for diagnosis and differential diagnosis of dermatosis.