排石颗粒与坦索罗辛治疗体外冲击波碎石后输尿管结石的疗效

Efficacy of Pai Shi Granule and Tamsulosin in the Treatment of Ureteral Calculi with External Shock Wave

目的探讨排石颗粒与坦索罗辛治疗体外冲击波碎石后输尿管结石的疗效。方法将2016年1月至2017年1月广东省东莞市高埗医院收治的104例体外冲击波碎石后输尿管结石患者作为研究对象,根据随机数字表法分为联合用药组与对照组,各52例。对照组患者采用常规止痛和多饮水等治疗,并给予排石颗粒;联合用药组患者则在对照组基础上采用坦索罗辛治疗。比较两组体外冲击波碎石后输尿管结石治疗总有效率;结石排出时间、肉眼血尿持续存在时间;患者肾绞痛发生率、复发率。结果联合用药组体外冲击波碎石后输尿管结石治疗总有效率明显高于对照组,差异有统计学意义(P<0.05);联合用药组结石排出时间、肉眼血尿持续存在时间均显著短于对照组,差异均有统计学意义(均P<0.05);联合用药组肾绞痛发生率、复发率均明显低于对照组,差异均有统计学意义(均P<0.05)。结论排石颗粒与坦索罗辛治疗体外冲击波碎石后输尿管结石疗效确切,两者联合可有效促进结石排出,缩短排石时间和血尿持续时间,降低肾绞痛发生率和复发率。

Objective To investigate the curative effect of Pai Shi granule and tamsulosin on ureteral calculi after extracorporeal shock wave lithotripsy.Methods From January 2016 to January 2017 in Guangdong province Dongguan City Gaobu hospital treated 104 cases of ureteral calculi after extracorporeal shock wave lithotripsy patients wererandomly divided into combined treatment group and control group,52 cases in each.The control group with routine analgesia and drinking water treatment,and given Paishi granule;combined treatment group in the control group based on the use of tamsulosin for the treatment of.The total effective rate of ureteral calculi after extracorporeal shock wave lithotripsy was compared between the two groups;the stone discharge time,gross hematuria duration, the incidence of renal colic and the recurrence rate were observed.Results The total effective rate of ureteral calculus was significantly higher than that of the control group（P〈0.05）.The time of stone bleeding in the combination group was shorter than that in the control group（P〈0.05）.The incidence of colic,recurrence rate was lower than the control group（P〈0.05）.Conclusion Pleurotus granulata and tamsulosin have an effective effect on the treatment of ureteral calculi with extracorporeal shock wave lithotripsy.The combination of both can effectively promote the excretion of stone, shorten the time of drainage and the duration of hematuria,reduce the incidence and recurrence rate of renal colic.