氯吡格雷联合血栓通注射液临床分组治疗不稳定型心绞痛的疗效观察及预后

The clinical grouping of clopidogrel combined thrombus injection in the treatment of unstable angina pectoris was observed and prognosis

目的探讨氯吡格雷联合血栓通注射液临床分组治疗不稳定型心绞痛(UA)患者的疗效及预后情况。方法选取东莞市虎门医院2016年6月至2017年1月心血管内科收治的UA患者80例为研究对象,按数字奇偶法分为观察组和对照组。对照组40例患者予以常规药物治疗,观察组40例患者在对照组基础上采用氯吡格雷联合血栓通注射液治疗。比较两组患者的治疗有效率及生命质量。结果观察组总有效率(97.5%)高于对照组(85.0%),差异有统计学意义(P<0.05);治疗前,两组日常生活活动能力(ADL)量表(Barthel指数)比较差异无统计学意义(P>0.05);治疗后,观察组Barthel指数优于对照组,差异有统计学意义(P<0.05)。结论采用氯吡格雷联合血栓通注射液治疗UA,疗效确切,可显著提高患者生命质量。

Objective To observe the curative effect and prognosis of the clinical group of clopidogrel combined thrombus injection in the treatment of unstable angina pectoris.Methods 80 cases of unstable angina（UA） patients admitted by Humen Hospital of Dongguan from June 2016 to January 2017 were divided into two groups observation group and control group.In the control group,40 patients were treated with conventional medicine,and 40 patients were treated with clopidogrel injection on the basis of control group.Compare the effectiveness of the two groups and the quality of life.Results The total effective rate of observation group（97.5%） was higher than the control group（85.0%）,and the difference was statistically significant（P〈0.05）.Before treatment,there was no statistically significant difference between the two groups of barthel index indexes（P〈0.05）.After treatment,barthel index indexes of the observation group was better than the control group（P 〉0.05）,and the difference was statistically significant. Conclusion The treatment of UA with clopidogrel combined thrombus injection is effective and can significantly improve the quality of life of patients.