摘要
目的 :研究芦丁与三价铬离子生成的芦丁铬络合物 (芦丁铬 )调节血脂作用。方法 :采用大鼠高血脂模型 ,观察芦丁铬对正常和高血脂大鼠的甘油三酯、胆固醇、HDL 胆固醇和LDL 胆固醇浓度的影响。结果 :芦丁铬能有效地升高正常和高血脂大鼠血铬水平 ,降低血清甘油三酯浓度 ;升高高血脂大鼠血清高密度脂蛋白水平 ;对高血脂大鼠血清总胆固醇和低密度脂蛋白也有降低趋势。结论
AIM: To study the effects of chromium rutin synthesized with rutin and chromium (Ⅲ) on metabolism of blood lipid. METHODS: The effects of chromium rutin on metabolism of blood lipid were evaluated by the changes of triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol in normal rats and the rats with high blood lipid. RESULTS: Chromium rutin could increase the blood chromium, decrease the concentrations of triglyceride, cholesterlo and LDL cholestelol,and increase the concentration of HDL cholesterol in normal and the rats with high blood lipid rats. CONCLUSION: Chromium rutin has an effect on the blood lipid in rats.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2002年第4期302-305,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
基金
宁夏大学科学研究基金资助项目 (№ 0 0 310 1)
关键词
芦丁铬
血脂
调节作用
高血脂症
chromium rutin
trace elements
blood chromium
blood Lipid
