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A comprehensive analysis of chromosomal anomalies in metaphase II spermatocytes from infertile patients

A comprehensive analysis of chromosomal anomalies in metaphase II spermatocytes from infertile patients
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摘要 Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosome characteristics at this stage. In this study, we have performed a comprehensive analysis of meiotic abnormalities in metaphase II spermatocytes combining Leishman＇s staining protocols and multiplex fluorescent in situ hybridization procedures. Results indicated that infertile individuals showed different susceptibilities to meiotic abnormalities in secondary spermatocytes without a preferentially effect on any particular chromosome. Dear Editor, The scarce number of secondary spermatocytes in human seminiferous tubules and the complexity of analyzing chromosomes at metaphase II are the main causes of the limited knowledge we have about chromosome characteristics at this stage. In this study, we have performed a comprehensive analysis of meiotic abnormalities in metaphase II spermatocytes combining Leishman＇s staining protocols and multiplex fluorescent in situ hybridization procedures. Results indicated that infertile individuals showed different susceptibilities to meiotic abnormalities in secondary spermatocytes without a preferentially effect on any particular chromosome.
作者 Zaida Sarrate Joan Blanco Oliver Valero Francesca Vidal
机构地区 Genetics of Male Fertility Group Servei d'Estadistica Aplicada
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2018年第1期105-106,共2页 亚洲男性学杂志（英文版）
分类号 Q343.2 [生物学—遗传学] TM923.321 [电气工程—电力电子与电力传动]
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共引文献4

Asian Journal of Andrology
2018年 第1期

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