除糖皮质激素及免疫抑制剂外的其他天疱疮治疗方法

Adjuvant therapy for pemphigus in addition to glucocorticoid and immunosuppressor

天疱疮是一种累及皮肤及黏膜的严重的慢性自身免疫大疱性疾病。目前主要运用糖皮质激素和免疫抑制剂治疗天疱疮,但在控制病情的同时,亦可引起高血压、骨髓抑制等不良反应。因此,根据患者的不同情况,常需选择其他治疗方法与糖皮质激素和(或)免疫抑制剂联合用药。本文就除糖皮质激素及免疫抑制剂治疗之外的其他天疱疮疗法作一综述。

Pemphigus is a severe, chronic, autoimmune bullous disease affecting the skin and mucous membranes. Recently, glucocorticoid and immunosuppressor are the most common treatments for pemphigus. However, these treatment may result in unfavorable effects, such as hypertension and marrow suppression, during treatment. Thus, the combination of other treatments with glucocorticoid and （or） immunosuppressor should be evaluated according to the patients＇ condition. In this article, we reviewed the non-glucocorticoid and non-immunosuppressor therapy.