基于Diels-Alder反应的智能分子印迹聚合物制备及性能表征

Preparation and Properties Characterization of Intelligent Molecularly Imprinted Polymer Based on Diles-Alder Reaction

采用热可逆的Diels-Alder(DA)反应制备分子印迹聚合物(MIP),以活化改性的含环氧基团硅胶为载体,以分子修饰β-环糊精作为功能单体,吲哚-3-乙酸(IAA)为模板分子,接枝呋喃型双烯体后交联聚合,得到含有温敏性DA反应亲双烯体结构组件的分子印迹聚合物,通过与双烯体发生DA反应得到新型结构的DA-MIP,通过温控实现IAA的智能性印迹.采用傅里叶变换红外光谱(FTIR)、核磁共振波谱(NMR)、扫描电子显微镜(SEM)表征原料、中间产物及终产物的结构;利用差示扫描量热(DSC)和热重分析法(TG)测试产物的热敏感性能;利用吸附实验比较MIP与DA-MIP的分子识别性能和特异性.结果表明,DA-MIP具有良好的热敏性,DA-MIP低温(60℃)不显示识别IAA作用,高温(140℃)显示特异性识别IAA作用,呈现出明显的温度敏感性,识别能力智能响应于环境刺激.温敏性智能DA-MIP的重复使用性能良好,识别目标分子的恢复率达84%.

Using activated epoxy group-containing silica gel as the carrier,the modification of β-cyclodextrin as functional monomer,and the indole-3-acetic acid（IAA） as template molecule,by Diels-Alder（DA）reaction with diene,a grafted furan-type diene was polymerized and crosslinked to obtain a molecularly imprinted polymer（DA-MIP）.The structure of raw material,intermediates and the molecularly imprinted polymer was characterized by Fourier transform infrared spectroscopy（FTIR）,cross polarization magic angle spinning ^（13）C nuclear magnetic resonance spectroscopy（CP/MAS13 C NMR） and scanning electron microscope（SEM）.The thermo-sensitivities were tested by differential scanning calorimetry（DSC） and thermal gravimetric analysis（TG）,adsorption performance and adsorption properties of the products were detected by adsorption experiment.The results showed the DA-MIP shows a good heat-reactivity.DA-MIP does not show the role of identification of IAA at low temperature（60 ℃）,but display specific identification of IAA at high temperature（140 ℃）,and showed obvious temperature sensitivity.Its temperature control is affected by environmental stimuli.The repetitive adsorption experiment of MIP show that the recovery rate is 84%.The results show that the MIP have a good reuse performance.