急性心力衰竭患者预后评估及其相关影响因素分析

Prognosis evaluation and correlated influencing factors of acute heart failure patients

目的:探讨急性心力衰竭(AHF)患者预后评估及其相关危险因素。方法:将210例急性心力衰竭患者依据随访结果分为事件组(45例)和非事件组(165例),收集各种临床资料,采用单因素比较和多因素Logistic回归来筛选可能影响AHF预后不良的危险因素。结果:AHF患者随访6个月内的预后不良率为21.43%(45/210);多因素分析显示,AHF预后不良的影响因素包括下肢水肿(OR=4.088)、心功能分级(OR=3.203)、LVEF(OR=0.535)、NT-proBNP(OR=1.234)及其cTnⅠ(OR=5.430)。结论:AHF患者的预后不良事件发生率仍然较高,其独立危险因素包括下肢水肿、心功能分级高、左心室射血分数低、较高水平的NT-proBNP和cTnⅠ,应综合考虑这些独立危险因素对患者进行早期评估。

[Objective]To explore prognosis evaluation and correlated influencing factors of acute heart failure(AHF)patients. [Method]210 AHF patients were divided into event group(45 cases) and non-event group(165 cases) according to following up result,and different clinical data was collected. Single factor comparison and multiple factors Logistic regression method were used to screen the risk factors of bad prognosis of AHF. [Result]The prognosis rate of AHF within 6 months after follow-up was 21. 43%(45/210). Multiple factors analysis showed that the influencing factors of bad prognosis of AHF included in edema of lower extremity(OR = 4. 088),cardiac functional grading(OR =3. 203),LVEF(OR = 0. 535),NT-proBNP(OR = 1. 234) and cTnⅠ(OR = 5. 430). [Conclusion]The rate of bad prognosis of AHF lies a high level. Its independent risk factors contain edema of lower extremity,cardiac functional grading,low level of LVEF,high levels of NT-proBNP and cTnⅠ. So we should comprehensively think of these independent risk factors and early evaluate patient's condition.