450例大肠息肉患者发病因素、发病特点及中医证型分布规律研究

Pathogenic Factors,Characteristics and Distribution of TCM Syndrome Analysis of 450 Patients with Colorectal Polyps

目的：探讨大肠息肉发病因素、发病特点及中医证候分布规律。方法：本研究采用横断面、回顾性研究方法,对大肠息肉患者一般资料、临床表现及中医四诊进行分析,总结该病的中医证候分布规律、发病特点及发病因素。结果：大肠息肉在中老年高发（92%）;临床症状表现不一,以腹痛腹胀腹泻多见（67.3%）;发病部位以乙状结肠最高（42%）;病理类型以腺瘤性息肉最高（62%）,且不同病理类型与年龄分布有显著差异,其中炎性息肉多发于中年人,错构瘤性息肉多发于青年人。样本中患者饮食习惯以肥甘厚味为主（78.67%）,饮酒是息肉发生的高危因素（P〈0.05）。证型分布以湿郁肠腑证最多见（77.33%）,好发于40~60岁年龄段（P〈0.05）,证型分布在各年龄段分布有显著差异,而与性别无相关性。结论：本研究提示饮食生活习惯及气候在大肠息肉的发病中具有重要地位。

Objective： To study the pathogenic factors,characteristics and distribution of TCM syndrome of colorectal polyps.Methods： This study used a cross-sectional,retrospective study method and analyzed general information,clinical manifestations and TCM four diagnostic methods of colorectal polyps and summarize the pathogenic factors,characteristics and distribution of TCM syndrome of the disease. Results： The colorectal polyps had high incidence in the elderly（92%）. The main clinical manifestations were abdominal distension and diarrhea with abdominal pain（67. 3%）. The highest incidence was in sigmoid colon. The highest pathologic type was adenoma polyp（62%） and different pathological types and age distribution were significantly difference（P 0. 05）,among multiple inflammatory polyps in the middle-aged,hamartomatous polyps was more common in young people. The habit of diet with fat was mainly 78. 67%. Alcohol is a risk factor for polyps（P 0. 05）. The damp in bowel syndrome was the highest（77. 33%）. The high incidence was in 40-60 years old peoples and there were significant differences in the distribution of each age group（P 0. 05）. There was no correlation between TCM syndrome types with gender（P 0. 05）.Conclusion： This study suggests that dietary habits and climate play important role in the pathogenesis of colorectal polyps.