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他克莫司联合小剂量糖皮质激素治疗肾病综合征效果分析 被引量:1

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摘要 目的:探讨他克莫司联合小剂量糖皮质激素治疗肾病综合征效果。方法:将2011年1月~2016年5月76例肾病综合征患者作为研究对象根据治疗方法分组,各38例。常规对照组采用环磷酰胺、足量激素进行治疗,治疗组则给予他克莫司联合小剂量糖皮质激素治疗。比较两组总有效率;尿频、脱发等不良反应发生率;干预前后24h尿蛋白、内生肌酐清除率、血清白蛋白。结果:治疗组总有效率高于常规对照组,P<0.05;治疗组尿频、脱发等不良反应发生率低于常规对照组,P<0.05;干预前两组24h尿蛋白、内生肌酐清除率、血清白蛋白相近,P>0.05;干预后治疗组24h尿蛋白、内生肌酐清除率、血清白蛋白优于常规对照组,P<0.05。结论:他克莫司联合小剂量糖皮质激素治疗肾病综合征效果确切,可有效改善病情和肾功能,减少不良反应,安全有效,值得推广。
作者 杨留杰
出处 《北方药学》 2018年第3期129-129,共1页 Journal of North Pharmacy
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