血脂康胶囊联合缬沙坦对高血压视网膜病变硬化期的短期效果

Short-term effect of Xuezhikang Capsules combined with Valsartan on sclerotic stage of hypertensive retinopathy

目的观察血脂康胶囊联合缬沙坦对高血压视网膜病变硬化期患者的短期临床疗效。方法选取山西省临汾市第四人民医院2012年1月~2015年7月收治的60例高血压性视网膜病变患者(106只患眼),按随机数字表法分为对照组和治疗组,每组各30例。两组均接受常规治疗,保证试验在患者血压值达到标准的情况下进行;观察组在此基础上给予血脂康胶囊。治疗8周后评价临床效果。结果治疗后两组收缩压和对照组舒张压均低于治疗前(P<0.05)。治疗组治愈率和总有效率高于对照组(P<0.05)。治疗组眼底小动脉痉挛、血管壁光反射改善情况优于对照组(P<0.05)。结论血脂康胶囊联合缬沙坦改善高血压视网膜病变硬化期视力、眼底血管荧光造影和高血压的短期效果较好。

Objective To observe the short-term effect of Xuzhikang Capsules combined with Valsartan in the treatment of patients with hypertensive retinopathy. Methods The subjects in 60 cases with 106 eyes were from the Fourth People′ s Hospital of Linfen from January 2012 to July 2015, and they were divided into control group and treatment group by random number table, with 30 cases in each group. The two groups were underwent routine treatment to ensure that the test was carried out with the patient′s blood pressure up to standard. The observation group was additionally treated with Xuezhikang Capsules. The clinical efficacy was evaluated at 8 weeks after treatment. Results After treatment, the systolic blood pressure in the two groups and diastolic blood pressure in the control group were decreased（P〈0.05）. The cure rate and total efficiency of treatment group were higher than those of control group（P〈0.05）. The mend matters of retinal arterial spasm and vascular wall reflex in treatment group were better than those in the control group（P〈0.05）. Conclusion The short-term effect of Xuzhikang Capsules combined with Valsartan in treating vision,fundus angiography and hypertension on sclerotic stage of hypertensive retinopathy is better.