基于“中医方证代谢组学”探讨中医防治心血管疾病研究进展

Research Progress of Prevention and Treatment of Cardiovascular Diseases by Traditional Chinese Medicine Based on the “Chinese Medicine Metabolomics”

目前,中医防治心血管疾病已成为心血管临床中的有效治疗方案。然而,在中医药现代化发展中,客观化、标准化的疗效及安全性评价体系是中医药发展存在的必然问题。中医方证代谢组学是21世纪兴起的新兴学科,其以中医病证为切入点,中药方剂为研究对象,利用代谢组学研究技术,形成鉴定病证生物标记物,建立中药方剂有效及安全性评价体系,探究中药方剂药效物质机制的应用科学。因此,该文将近年来,以＂中医方证代谢组学＂理论体系为核心导向,将中医防治心血管疾病的研究进展做一简要概述,旨在为中医防治心血管疾病提供理论依据,为中医药现代化发展提供新的视野和思路。

At present,Chinese medicine prevention and treatment of cardiovascular disease has become an effective clinical treatment of cardiovascular clinical.However,in the development of Chinese medicine modernization,objective and standardized efficacy and safety evaluation system is the inevitable problem of the development of Chinese medicine.Chinese medicine metabolomics is the emerging subject of the 21st century,it is a applied science,which is regared the traditional Chinese medicine disease and syndrome as the starting point,the traditional Chinese medicine prescription as the research object,using metabolomics research techniques,forming the identification of biological markers for the disease and syndrome,the establishment of traditional Chinese medicine prescription effective and safety evaluation system,to explore the traditional Chinese medicine prescription pharmacological mechanism.Therefore,this article focuses on the research progress of traditional Chinese medicine preventing cardiovascular disease in recent years to make a brief overview,aims to provide theoretical basis for the prevention and treatment of cardiovascular disease in Chinese medicine,and provide new vision and ideas for the modernization of Chinese medicine.