注射用头孢哌酮钠舒巴坦钠联合盐酸莫西沙星氯化钠注射液治疗重症肺炎的效果观察

The curative effect detection of treatment severe pneumonia by Sulperazon union Avelox

目的探讨注射用头孢哌酮钠舒巴坦钠联合盐酸莫西沙星氯化钠注射液治疗重症肺炎的疗效情况。方法选择2013年3月~2016年3月在我院收治的68例患者,依据治疗措施不同分为对照组(单独注射用头孢哌酮钠舒巴坦钠治疗)30例和联合治疗组(注射用头孢哌酮钠舒巴坦钠联合盐酸莫西沙星氯化钠注射液治疗)38例。观察两组患者治疗前后血浆指标以及白细胞计数水平情况,观察两组患者临床疗效、不良反应发生情况。结果两组患者治疗前PCT、WBC、CRP,差异无统计学意义(P>0.05),治疗后对照组和联合治疗组患者PCT、WBC、CRP均低于治疗前,差异有统计学意义(P<0.05);联合治疗组患者治疗后PCT、WBC、CRP均低于对照组,差异有统计学意义(P<0.05);联合治疗组患者临床总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者恶心、腹泻、头晕不良反应发生率差异无统计学意义(P>0.05)。结论注射用头孢哌酮钠舒巴坦钠联合盐酸莫西沙星氯化钠注射液治疗患者的临床效果明显,可明显降低PCT、WBC、CRP水平,不良反应少,值得临床推广应用。

Objective To approach curative effect of treatment severe pneumonia by Sulperazon union Avelox. Methods 68 patients with severe pneumonia admitted to our hospital from March 2013 to March 2016 were selected,According to the different treatment measures were divided into the control group （Sulperazon alone） 30 cases and the combined treatment group （Sulperazon combined with Avelox treatment）38 cases.The plasma index and white blood cell count of two groups of patients with severe pneumonia before and after treatment were observed, and the clinical efficacy and adverse reactions of two groups of patients with severe pneumonia were observed.Results There was no significant difference in pct,WBC and CRP between the two groups before treatment （P〉0.05）.After treatment, the levels of pct,WBC and CRP in the control group and the combined treatment group were lower than those before treatment （P〈0.05）.Pct, WBC and CRP in the combined treatment group were significantly lower than those in the control group （P〈0.05）.The clinical total effective rate of severe pneumonia patients in the combined treatment group was higher than that in the control group, and the difference was statistically significant （P〈0.05）.There was no significant difference in the incidence of nausea, diarrhea and dizziness between the two groups （P〉0.05）.Conclusion The treatment severe pneumonia by Sulperazon union Avelox,clinical effects is obviously,PCT and WBC,CRP are obviously decreasing,untoward effect is little,it is worth to be used.