宫颈癌扩散峰度成像检查的可重现性研究

Reproducibility of diffusional kurtosis imaging measurement in uterine cervical carcinoma

目的评估磁共振扩散峰度成像(DKI)应用于宫颈癌检查的可重现性。方法选取我院2016年6~12月的10例宫颈癌患者和10名健康志愿者,于相隔24 h^14 d进行2次轴位DKI扫描,测量峰度参数K以及扩散参数D,并用SPSS 19.0软件进行统计学分析。结果总受试者、志愿者和宫颈癌患者参数D的组内变异系数(ICC)分别为0.899、0.935和0.828,参数K的ICC分别为0.870、0.871和0.877。总受试者、志愿者和宫颈癌患者参数D的变异系数分别为17.23%、16.43%和16.51%,参数K的变异系数分别为17.85%、20.16%和12.28%。结论 DKI序列在检测宫颈组织水分子非高斯扩散方面具有较好的可重现性。

Objective To evaluate the reproducibility of magnetic resonance imaging （MRI） diffusional kurtosis imaging （DKI） in detecting of cervical carcinoma.Methods 10 patients and 10 healthy volunteers in our hospital from June to December in 2016 were selected and underwent duplicate MRI scans by using DKI with an interval of 24 hours to 14 days.The metric K and D were obtained from parametric maps and evaluated by statistical software SPSS 19.0.Results The D value of intra group variation coefficient （ICC） of the total subjects,volunteers, and cervical cancer patients were 0.899,0.935 and 0.828,respectively.The ICC of parameter K was 0.870,0.871 and 0.877,respectively.The coefficients of variation of the D in the total subjects,the volunteers and the patients with cervical cancer were 17.23%,16.43% and 16.51%,respectively.The coefficients of variation of parameter K were 17.85%,20.16% and 12.28%,respectively.Conclusion DK imaging sequence appears reproducible in detecting the non Gauss diffusion of water molecules in cervical carcinoma.