老年特发性全面性癫痫病人的记忆障碍水平分析

Degree of memory impairment in the elderly patients with idiopathic epilepsy

目的分析老年特发性全面性癫痫病人的记忆障碍水平。方法选取2011年6月至2016年6月期间我院收治的72例老年特发性全面性癫痫病人作为观察组,同时选取同期来我院进行健康检查的72例老年健康志愿者作为对照组。对比2组病人简易智力状态检查量表(MMSE)评分、情景记忆知晓感(FOK-EM)、语义记忆知晓感(FOK-SM)。结果观察组病人的记忆力、定向力、回忆能力、注意力和计算力、语言能力、MMSE总分均显著低于对照组,差异具有统计学意义(P<0.05)。2组病人FOK-EM的线索回忆成绩、再认成绩、否定判断/错误再认、高估差异无统计学意义(P>0.05)。观察组病人FOK-EM的判断准确率、肯定判断/正确再认低于对照组,低估高于对照组,差异具有统计学意义(P<0.05)。2组病人FOK-SM的再认成绩、判断准确率、肯定判断/正确再认、否定判断/错误再认、高估、低估差异无统计学意义(P>0.05)。观察组病人FOK-SM的线索回忆成绩显著低于对照组,差异具有统计学意义(P<0.05)。结论老年特发性全面性癫痫病人情景记忆表现出对再认能力的低估,语义记忆表现出线索回忆能力的降低。

Objective To analyze the degree of memory impairment in the elderly patients with idiopathic epilepsy. Methods Seventy-two elderly patients with idiopathic generalized epilepsy from June 2011 to June 2016 were enrolled as the observation group,and 72 cases of healthy elderly volunteers receiving health examination during the same period were enrolled as the control group. The scores of mini-mental state examination scale（ MMSE）,situational memory awareness（ FOK-EM） and semantic memory awareness（ FOK-SM） were compared between the two groups. Results Memory,orientation,recall memory,attention and computing power,language ability,total score of MMSE in observation group were significantly lower than those in control group（ P 0. 05）. The accurate rate of judgment and the rate of affirmative judgment/correct recognition were significantly lower,while the underestimating rate was significantly higher in FOK-EM in the observation group than those in the control group（ P0. 05）. Clue recall in FOK-SM＇s recognition score in the observation group was significantly lower than that in the control group（ P 0. 05）. Conclusions The episodic memory of the elderly patients with idiopathic comprehensive epilepsy show an underestimation of recognition ability,and the semantic memory show a reduction in the recall ability.