氯米芬与来曲唑治疗多囊卵巢综合征促排对比

Clomiphene and letrozole in the treatment of polycystic ovary syndrome cupai contrast

目的:探究对比氯米芬与来曲唑治疗多囊卵巢综合征不孕患者中促排卵的临床效果。方法:研究的分析对象为80例多囊卵巢综合征患者,将此80例患者分为观察组和对照组,划分标准为治疗方法的不同,观察组患者给予来曲唑治疗,对照组患者给予氯米芬治疗,比较两组患者的排卵率、周期妊娠率、卵泡发育情况、子宫内膜厚度以及天然雌激素的添加情况。结果:两组患者的排卵率、周期妊娠率、卵泡发育情况相比较,差异均无统计学意义(P>0.05),观察组患者的内膜厚度大于对照组,且需添加雌激素的周期相较于对照组来说明显减少,两组差异有统计学意义(P<0.05)。结论:应用来曲唑治疗多囊卵巢综合征可以有效保护子宫内膜,促进排卵,值得临床推广。

Objective：A comparative study of clomiphene citrate and letrozole in the treatment of polycystic ovary syndrome specific clinical effect of ovulation in infertile patients.Methods：80 cases of polycystic ovary syndrome patients as the research object, the patients were divided into observation group and control group, the observation group was treated with letrozole treatment, the control group was treated with clomiphene added treatment, compared two groups of patients with ovulation rate, pregnancy the rate of follicular development, endometrial thickness and natural estrogen.Results：two groups of patients with ovulation rate, pregnancy rate and follicular development compared with no statistical significance （P〉 0.05）, endometrial thickness in the observation group than the control group, the cycle and the need to add estrogen significantly less than the control group, there was a significant difference between the two, there was statistical significance （P〈 0.05）.Conclusion： letrozole in the treatment of polycystic ovary syndrome can effectively protect the endometrium, promote ovulation, It is worthy of clinical application and promotion.