近16年中药复方治疗儿童多动症用药规律分析

Study on Medication Regularity of Chinese Compound Prescriptions in Treatment of Attention Deficit Hyperactivity Disorder in Recent 16 Years

目的 :研究近16年中药复方治疗儿童多动症的用药规律,为临床用药提供参考。方法:收集整理2000~2015年国内公开发表的中药复方治疗儿童多动症的文献,对中药复方的用药种数、种类、频次、性味、归经采用频数分步法进行统计,总结用药规律及特点。结果:63首复方总共使用15类113种中药,使用频次最高的前10位(含11味药)依次为:远志、石菖蒲、熟地黄、牡蛎、龙骨、龟甲、白芍、五味子、茯苓、山药、山萸肉;前5位药物类别依次为补虚药、清热药、安神药、平肝熄风药、收涩药;药性以温为最,其次为凉、寒、平;药味以甘味为最,其次为苦、辛、咸、酸;用药归经总频次以肝经为最,其次为心、肾、脾、肺。结论:中医治疗儿童多动症以补虚、安神、清热、平肝为主,兼以健脾。

Objective：To study the medication regularity of Chinese compound prescriptions in treatment of attention deficit hyperactivity disorder（ADHD） in recent 16 years,so as to provide reference for clinical medication. Methods：By collecting and analyzing the literature about Chinese compound prescriptions in treatment of ADHD which published from 2000 to 2015 in China,the quantity,kind,frequency,property and taste ,meridian entries of medicines used in the prescriptions were analyzed and calculated out by frequency distribution method,and the regularities and characteristics of medication were summarized. Results： In the eligible literature,there were 63 Chinese compound prescriptions containing 113 kinds and 15 categories of Chinese medicine. The top 10（containing 11 kinds of medicine） frequently used medicines were Yuanzhi（Poly- galae Redix）, Shichangpu （Acori tatarinowii Rhizoma）, Shudihuang （Rehmanniae Radix Praeparata）, Mull （Ostreae Concha）, Longgu （Fossil Fragment）, Guijia （Testudinis Carapax et Pastrum）, Baishao （Paeoniae Radix Alba）, Wuweizi （Schisandrae chinensis Fructus）, Fuling （Poria）, Shanyao （Dioscoreae Rhizoma） and Shanyurou （Corni Fructus）. The top five kinds of frequently used midicines were tonifying and replenishing medicines, heat-clearing medicines, tranquilizing medicines, liver-pacifying and wind-extinguishing medicines, astringent medicines. In the order of the frequency of medicine property,it gone warm,cool,cold and mild. In the or- der of the frequency of medicine taste,it gone sweet,bitter,pungent,sah and sour. In the order of the fre- quency of total meridian entry,it gone liver meridian,heart meridian,kidney meridian,spleen meridian and lung meridian. Conclusion：The main therapies in treating ADHD are tonifying,tranquilizing the spirit,clearing the heat and pacifying the liver,with strengthening the spleen as the supplement.