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冠心病介入治疗中氯吡格雷的应用及临床可行性研究 被引量:1

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摘要 目的探讨冠心病介入治疗中氯吡格雷的应用及临床可行性。方法将2016年2月—2017年3月新郑市人民医院收治的90例冠心病介入治疗患者作为对象根据随机信封法分组,各有45例。标准剂量组采用标准剂量氯吡格雷进行治疗,大剂量组采用大剂量氯吡格雷进行治疗。比较两组冠心病介入治疗后再狭窄发生率;出血等不良反应发生率;干预前后患者血小板聚集率、TXB2、PLT计数。结果大剂量组冠心病介入治疗后再狭窄发生率低于标准剂量组,P<0.05;大剂量组出血等不良反应发生率和标准剂量组之间无显著差异,P>0.05;干预前两组血小板聚集率、TXB2、PLT计数相近,P>0.05;干预后大剂量组血小板聚集率、TXB2、PLT计数优于标准剂量组,P<0.05。结论冠心病介入治疗中氯吡格雷的应用及临床可行性高,可有效预防血栓形成和再狭窄,改善血液流变学特点,不良反应少,安全有效,值得推广。
作者 王广军
机构地区 新郑市人民医院
出处 《医药论坛杂志》 2017年第12期146-147,共2页 Journal of Medical Forum
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