米索前列醇在产后宫缩乏力性出血产妇中的防治效果

Prevention and treatment effect of misoprostol in puerpera with postpartum uterine atony hemorrhage

目的探讨米索前列醇在产后宫缩乏力性出血产妇中的防治效果。方法回顾性分析厦门市第五医院2014年12月—2016年12月收治的产后宫缩乏力性出血产妇156例,随机将产妇分为对照组与观察组,每组78例。对照组产妇予以缩宫素治疗,观察组产妇予以米索前列醇联合缩宫素治疗。比较两组产妇出血率,产后0.5、2、24 h出血量。结果观察组产妇出血率为5.13%,低于对照组的32.05%(P<0.05)。两组产妇产后0.5 h出血量比较,差异无统计学意义(P>0.05);观察组产妇产后2、24 h出血量少于对照组(P<0.05)。结论米索前列醇对产后宫缩乏力性出血的预防和治疗效果明显,可有效降低产妇出血率和出血量。

Objective To investigate the prevention and treatment effect of misoprostol in puerpera with postpartum uterine atony hemorrhage.Methods A total of 156 cases of puerpera with postpartum uterine atony hemorrhage were selected from December 2014 to December 2016 in the Fifth Hospital of Xiamen,which were randomly divided into the control group and observation group,78 cases in each group.The control group was treated with oxytocin,observation group was treated with misoprostol combined with oxytocin.The bleeding rate,postpartum 0.5,2,24 h bleeding volume were compared between the two groups.Results The bleeding rate of observation group was 5.13%,which was lower than that of control group（32.05%）（P〈0.05）.There was no significant difference in postpartum 0.5 h bleeding volume between the two groups（P〉0.05）;The bleeding volume of postpartu 2 h and 24 h in observation group were less than control group（P〈0.05）.Conclusion The effect of misoprostol on the prevention and treatment of postpartum uterine atony bleeding is obvious,it can effectively reduce the rate of bleeding and bleeding volume.